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Immunodeficiency and autoimmune disease may occur concomitantly in the same individual. Some of the immunodeficiency syndromes, especially humoral defects are associated with autoimmune disorders. Hem...
In dermal and mucosal defects, the most important natural defence mechanism against infections is secretory IgA (1). Juvenile rheumatoid arthritis (JRA) accompanied by chronic arthritis together wit...
Background: IgA deficiency (IgAD) is the most common immunodeficiency, however the pathogenesis in most cases of IgAD is unknown. There are 2 subclasses of IgA, IgA1 and IgA2, and its heavy chains are...

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