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研究首次提出外周血ctDNA对儿童AML作用
白血病 血液学 形态学 免疫学
2024/1/29
近日，中国医学科学院血液病医院（中国医学科学院血液学研究所）竺晓凡主任医师和阮敏副主任医师团队在Clinical Cancer Research在线发布研究论文，在国际上首次提出外周血ctDNA是儿童AML患者MRD水平监测的重要标志。
髓系肉瘤是一种少见的血液系统恶性肿瘤，常伴随急性髓系白血病（AML）或作为AML复发时的首要表现。本科2010年11月收治1 例患者以睾丸髓系肉瘤起病，1 个月后进展为标准的AML。该患者接受异基因干细胞移植后骨髓达完全缓解，但移植后5 个月出现右肾上腺占位。综合了影像科、PET-CT 室、放疗科、泌尿肿瘤科的诊治意见，给该患者行右肾上腺射波刀放疗。随访至2013年3 月，该患者无论骨髓还是髓外均...
针对短采样宽带信号近似最大似然（approximated maximum likelihood,AML）方位估计计算量大的问题，将马尔科夫链〖CD*2〗蒙特卡罗方法与近似最大似然方位估计相结合，提出一种基于MetropolisHastings抽样的近似最大似然方位估计方法（AMLMH）。该方法将AML算法的空间谱函数作为信号的概率分布函数，并利用MetropolisHastings抽样方法...
Textural and Compositional Evidence for Magma Mixing in the Evolution of the Çamlıdere Volcanic Rocks (Galatean Volcanic Province), Central Anatolia, Turkey
Ç amlı dere Turkey zoning sieved texture reaction texture magma mixing
2009/7/7
The Çamlıdere area, in the Galatean Volcanic Province (Ankara), Turkey, is composed of rhyolitic, andesitic, trachytic, dacitic and locally basaltic rocks. The older volcanic rocks in the...
Adhesion of Beta1 Integrin to Fibronectin Regulates CAM-DR Phenotype via p21WAF1/cip1 in HL60 Acute Myeloid Leukemia (AML) Cells
Apoptosis CAM-DR fibronectin cell cycle
2009/6/16
Aims: Drug resistance is a major obstacle for a successful cancer therapy. Cell adhesion mediated drug resistance (CAM-DR) is a novel type of drug resistance and generated via interaction of cancer ce...
介绍了自行研制用于环境监测的车载式激光雷达(AML-1)系统及典型特点，其在测量气溶胶时不但可以全天候探测，还可以从不同仰角进行测量，对实现连续、实时、大范围监测大气污染有着重要的意义。结合该激光雷达的特点，从垂直、斜程、二维扫描等方面分别给出了该系统探测气溶胶时的典型结果和时空分布图，总结了AML-1车载测污激光雷达系统在测量气溶胶时的优越性和意义。
Treatment of acute myeloid leukemia (AML):Recent results and new directions
Acute myeloid leukemia hematopoietic stem cell transplantation
2010/5/7
Acute myeloid leukemia (AML) is a major indication for hematopoietic stem cell transplantation (HSCT). Here we describe more in general the present status and new directions in the therapy for AML.
三氧化二砷对非M_3的AML及ALL细胞Fas和FasL蛋白影响的研究
三氧化二砷 凋亡 Fas FasL 非M3的AML及ALL
2014/1/16
了解As2 O3 对非M3 的急性髓性白血病 (AML)及急性淋巴细胞性白血病 (ALL)细胞Fas、FasL蛋白的影响。方法 将非M3 的AML细胞和ALL细胞体外与不同浓度As2 O3 共同培养 ,通过细胞计数、细胞活力的判定并利用流式细胞仪检测DNA、Fas和FasL蛋白的变化 ,来观察As2 O3 对上述细胞的细胞活力、增殖周期及Fas、FasL蛋白的影响。结果 随着As2 O3 浓度由 ...
Treatment of acute myeloid leukemia (AML): Recent results and new directions
Treatment acute myeloid leukemia (AML) Recent results new directions
2010/4/22
Treatment of acute myeloid leukemia (AML): Recent results and new directions。
AML-M_5细胞诱导TCR Vβ T细胞克隆性增殖研究
TCRVβ基因 克隆性 T细胞培养 基因扫描
2014/1/18
了解急性髓细胞白血病 (AML)M5亚型细胞诱导T细胞的TCRVβ亚家族限制性利用和克隆性增殖情况。方法 采用混合淋巴细胞 /肿瘤细胞培养 (MLTC)方法 ,用AML M5细胞体外诱导供者外周血和脐血的T细胞增殖 ,用RT PCR扩增经MLTC前后获得细胞的 2 4个TCRVβ亚家族基因的互补决定区 (CDR3) ,了解病人各Vβ亚家族的利用情况。并经基因扫描分析确定M5细胞诱导的T细胞克隆性特...
The Moss Flora of Ankara - Kızılcahamam - Çamkoru and Çamlıdere Districts
Bryophytes Moss Flora Kı zı lcahamam Ç amkoru Ç amlı dere
2010/3/22
In this study carried out in Ankara-Kızılcahamam Çamlıdere and Çamkoru districts, 82 taxa were identified by the authors. These belong to 20 families and 42 genera of bryo...
Epoche in Chironomidae (Diptera) Larvae in the Streams Beşik and Çamlıca, a Part of the Southern Sakarya River System
Ephemeroptera Chironomidae Epoche Larva
2010/4/1
On Ephemeranymphs, in the streams Besik and Çamlica, a part of the Sakarya river system, Chironomidaelarvae were found to live epochally. These are Epoicocladius flavens on Ecdyonurus venosus a...